USING MACHINE LEARNING METHODS TO STUDY THE TUMOUR MICROENVIRONMENT AND ITS BIOMARKERS IN OSTEOSARCOMA METASTASIS

Using machine learning methods to study the tumour microenvironment and its biomarkers in osteosarcoma metastasis

Background: The long-term prognosis for patients with osteosarcoma (OS) metastasis remains unfavourable, highlighting the urgent need for research that explores potential biomarkers using innovative methodologies.Methods: This study explored potential biomarkers for OS metastasis by analysing data from the Cancer Genome Atlas Program (TCGA) and Gen

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Study on the Imbibition Damage Mechanisms of Fracturing Fluid for the Whole Fracturing Process in a Tight Sandstone Gas Reservoir

Tight sandstone gas is a significant unconventional natural gas resource, and has been exploited economically mostly through the application of hydraulic fracturing technology in recent decades.However, formation damage occurs when fracturing fluid percolates into the pores inside sandstones through imbibition driven by capillary pressure during fr

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From the Patrimonial to the Civic Standard of Music for All: The Transformations of Musical Institutions in Nineteenth-Century Bohemia and the Problems of Their Music-Historical Interpretation

The topic of institutionalisation of musical life in the nineteenth century invites a new perspective on the transformation processes in multinational Austria.The Kingdom of Bohemia is an example of a bilingual country in which the development of civil institutions together with a national UHF VHF Antenna Diplexor movement was quite successful.Thes

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Diagnostic and therapeutic dilemma in Stevens–Johnson syndrome-like acute graft-versus-host disease after liver transplantation: A case report

BackgroundAcute graft-versus-host disease (aGVHD) is a severe and fatal complication after orthotopic liver transplantation (OLT).Clinical manifestations of severe aGVHD can resemble drug-induced Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), and there are also various medications, such as antibiotics and immunosuppressants, use

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Wrapping the stump of the gastroduodenal artery using the ligamentum teres hepatis during laparoscopic pancreaticoduodenectomy: a center’s preliminary experience

Abstract Background The present study aims to assess the preliminary outcomes of the effectiveness of wrapping the ligamentum teres hepatis (LTH) around the gastroduodenal artery stump for the prevention of erosion hemorrhage after laparoscopic pancreaticoduodenectomy (LPD).Methods We Heat Sink reviewed 247 patients who had undergone LPD between Ja

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